产品货号:
Z31355
中文名称:
CUL4A抗体
英文名称:
Anti-CUL4A Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-CUL4A Antibody |
指标别名 | CUL 4A;CUL4A;CUL4A-Specific;cullin 4A |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | WB |
基因名称 | CUL4A |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human Cullin4A Core component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins.As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. |
实际分子量 | 88KD |
成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Cullin-4A is a protein that in humans is encoded by the CUL4A gene.It belongs to the cullin family of ubiquitin ligase proteins and is highly homologous to the CUL4B protein.CUL4A regulates numerous key processes such as DNA repair,chromatin remodeling,spermatogenesis,haematopoiesis and the mitotic cell cycle.As a result,CUL4A has been implicated in several cancers and the pathogenesis of certain viruses including HIV.Interestingly,a component of a CUL4A complex,Cereblon,was discovered to be a major target of the teratogenic agent thalidomide. |
Uniprot ID | Q13619 |
推荐稀释比 | Western blot (WB) 1:500~2000 |
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